Statistical thinking is the foundation upon which all quantitative analysis is built. In financial markets, nothing is certain, so every conclusion must be expressed in terms of probability. When a quantitative analyst says a strategy "works," they mean it has produced statistically significant positive returns across a meaningful sample of historical data, not that it will profit on every trade. Understanding this distinction is critical for anyone entering the quantitative investing space.
The most fundamental statistical concepts for market analysis are mean, variance, and correlation. The mean return of an asset tells you the central tendency of its performance. Variance (or its square root, standard deviation) tells you how widely returns are dispersed around that mean. Correlation tells you how two assets move relative to each other. These three measures form the basis of portfolio construction. Markowitz showed that by combining assets with low correlations, an investor can achieve higher risk-adjusted returns than holding any single asset.
Distributions of financial returns have properties that confound simple statistical models. Stock returns exhibit fat tails, meaning extreme events occur more frequently than a normal distribution would predict. The 2008 financial crisis, for example, involved daily moves that a Gaussian model would predict to occur once in several billion years. Returns also exhibit skewness, and volatility tends to cluster: large moves in either direction are followed by more large moves, a phenomenon formalized by Robert Engle's ARCH models.
Hypothesis testing provides the framework for evaluating whether an observed pattern is real or simply noise. The p-value, which represents the probability of observing results at least as extreme under the null hypothesis, is the standard metric. In academic finance, a p-value below 0.05 is typically required for significance. However, given the vast number of patterns tested across thousands of researchers and datasets, many published anomalies may be artifacts of data mining. Harvey, Liu, and Zhu (2016) argued that a t-statistic of 3.0 (rather than the traditional 2.0) should be the threshold for new factor discoveries.
Regression analysis is the workhorse tool for quantitative finance. Simple linear regression allows you to estimate the relationship between a dependent variable (like stock returns) and an independent variable (like market returns). Multiple regression extends this to many variables simultaneously. The Capital Asset Pricing Model is essentially a regression equation where a stock's excess return is regressed against the market's excess return, with the slope coefficient being beta.